Journal of Forensic Dental Sciences
IAFO CONFERENCE 2018 GOA - http://iafo2018goa.com/ Users Online: 514 
Home Print this page  Email this page Small font size Default font size Increase font size
Wide layoutNarrow layoutFull screen layout
  Home | About JFDS | Editorial Board | Search | Ahead of print | Current Issue | Archives | Instructions | Subscribe | Online submission | Contact us | Advertise | Login 
ORIGINAL ARTICLE
Year : 2014  |  Volume : 6  |  Issue : 2  |  Page : 132-138

Molecular sex identification of dry human teeth specimens from Sokoto, Northwestern Nigeria


1 Department of Anatomy, College of Health Sciences, Usmanu Danfodiyo University, Sokoto, Nigeria
2 Department of Paediatrics, College of Health Sciences, Usmanu Danfodiyo University, Sokoto, Nigeria
3 Department of Medical Molecular Genetics, Division of Human Genetics and Genome Research, National Research Centre, Cairo, Egypt

Correspondence Address:
A D Zagga
Department of Anatomy, College of Health Sciences, Usmanu Danfodiyo University, P. M. B. 2346, Sokoto, Nigeria

Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0975-1475.132544

Rights and Permissions

Background: The advent of molecular techniques has revolutionized the ability of scientists to estimate the sex of individuals. Forensic odontology plays an important role in establishing the sex of victims with bodies mutilated beyond recognition due to major disaster. The genetic difference between males and females is defined by the presence or absence of the Y-chromosome. The use of alphoid-repeat primers in sex estimation was first applied on dried blood. Generally, the X, Y alphoid repeats blind test attest to the accuracy of genetic testing, and also point the potential for occasional error in morphometric sexing. Aim: To estimate genetic sex of dry human teeth specimens from Sokoto, Northwestern Nigeria, using polymerase chain reaction (PCR). Materials and Methods: A single-blind study of DNA analysis for sex estimation of nine dry human teeth specimens from Sokoto, Northwestern Nigeria, through PCR, using alphoid repeats primers, was undertaken. Results: The genetic sex of each group of the teeth samples were accurately (100%) identified. For each group of teeth, PCR Sensitivity = 100%, Specificity = 0%, Predictive value of positive test = 100%, Predictive value of negative test = 0%, False positive rate = 0%, False negative rate = 0%, Efficiency of test = 100%. Fisher's exact probability test P = 1. Z-test: z- and P values were invalid. Conclusion: This study has demonstrated the successful use of alphoid-repeat primers in genetic sex identification of human dry teeth samples from Sokoto, Northwestern Nigeria. This is the first known study estimating the sex of human dry teeth specimens by means of PCR in Nigeria. There is need for further studies in Nigeria to complement the findings of this study.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1749    
    Printed60    
    Emailed0    
    PDF Downloaded245    
    Comments [Add]    

Recommend this journal